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The reaction mechanism for roGFP2(S 2 ) as a model non-glutathione disulfide substrate resembles the first part of the GSH-dependent reduction of the sulfenic acid of human peroxiredoxin 6 that is catalyzed by glutathione transferase P1-1 (which shares several structural features with glutaredoxins) 7,80,81,82

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Behav Res Therapeutic Indications Int J Tryptophan Res 2:4560 [DOI] [PMC free article] [PubMed] [Google Scholar] Ristow M, Zarse K (2010) How increased oxidative stress promotes longevity and metabolic health: the concept of mitochondrial hormesis (mitohormesis)